rs4415084

A SNP on chromosome 5. Its most notable genotype is C;C.

Gene
None listed
Location
Chr 544,662,413 (GRCh38)
Highest magnitude
0.0Typical
Tested on
23andMe, AncestryDNA, FamilyTreeDNA
Minor allele frequency
49%

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. C;CMost notableNot ratedNo summary available.Typical · 0.021% of people

On SNPedia: (C;C). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 11 HapMap populations.

  • AverageC;C 21%
  • European ancestry (Utah)C;C 38%
  • Han Chinese (Beijing)C;C 30%
  • Japanese (Tokyo)C;C 19%
  • Yoruba (Nigeria)C;C 12%
  • African ancestry (Southwest US)C;C 11%
  • Chinese (Denver)C;C 18%
  • Gujarati IndianC;C 24%
  • Luhya (Kenya)C;C 15%
  • Mexican ancestry (Los Angeles)C;C 28%
  • Maasai (Kenya)C;C 12%
  • TuscanC;C 31%

Conditions, medicines and genes

Notes

From SNPedia

Notes

rs4415084 and rs10941679 confer risk for estrogen receptor breast cancer (ER)-positive tumors (OR = 1.27, P = 2.5E-12 for rs10941679) based on a study of 6,145 cases. From a DeCode user report, the risk allele appears to be T; this T;T individual reportedly has a 1.19x increased risk of breast cancer. the two risk SNPs reported in the European population were neither associated with breast cancer risk in our Chinese population A multistage genome-wide association study in breast cancer identifies two new risk alleles at 1p11.2 and 14q24.1 (RAD51L1). Leveraging genetic variability across populations for the identification of causal variants.

Source and license

Adapted from rs4415084 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.