rs447529

A SNP in the PALB2 gene on chromosome 16. Its most notable genotype is G;G: Benign variant

Gene
PALB2
Location
Chr 1623,622,102 (GRCh38)
Highest magnitude
0.0Typical
Tested on
23andMe
Minor allele frequency
15%

Genotypes

Plus strand, as in 23andMe and AncestryDNA files.

  1. G;GMost notableNot ratedBenign variantTypical · 0.02% of people
  2. C;GGoodbenign variantTypical · 0.026% of people
  3. C;CGoodcommon in clinvarTypical · 0.072% of people

SNPedia records rs447529 on the minus strand: (C;C), (C;G), (G;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 4 HapMap populations.

  • AverageG;G 2% C;G 26% C;C 72%
  • European ancestry (Utah)G;G 0% C;G 14% C;C 86%
  • Han Chinese (Beijing)G;G 0% C;G 29% C;C 71%
  • Japanese (Tokyo)G;G 2% C;G 21% C;C 77%
  • Yoruba (Nigeria)G;G 5% C;G 40% C;C 55%

Other PALB2 SNPs

All PALB2 SNPs

Source and license

Adapted from rs447529 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.