rs448740

A SNP in the FCGR3B gene on chromosome 1. Its most notable genotype is C;T: one of the differences in NA1 and NA2 neutrophil alloantigens

Gene
FCGR3B
Location
Chr 1161,629,903 (GRCh38)
Highest magnitude
0.5Typical
Tested on
23andMe

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. C;TMost notableBadone of the differences in NA1 and NA2 neutrophil alloantigensTypical · 0.560% of people
  2. T;TGoodcommon in clinvarTypical · 0.00% of people

On SNPedia: (C;T), (T;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in one HapMap population.

  • Yoruba (Nigeria)C;T 60% T;T 0%

Notes

From SNPedia

Notes

C;T

see discussion in OMIM 610665.0001

Source and license

Adapted from rs448740 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.