rs4623951

A SNP in the DAO gene on chromosome 12. Its most notable genotype is T;T: common/normal

Gene
DAO
Location
Chr 12108,878,275 (GRCh38)
Highest magnitude
0.0Typical
Tested on
23andMe, AncestryDNA, FamilyTreeDNA
Minor allele frequency
29%

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. T;TMost notableGoodcommon/normalTypical · 0.056% of people

On SNPedia: (T;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 11 HapMap populations.

  • AverageT;T 56%
  • European ancestry (Utah)T;T 36%
  • Han Chinese (Beijing)T;T 60%
  • Japanese (Tokyo)T;T 71%
  • Yoruba (Nigeria)T;T 62%
  • African ancestry (Southwest US)T;T 60%
  • Chinese (Denver)T;T 72%
  • Gujarati IndianT;T 49%
  • Luhya (Kenya)T;T 55%
  • Mexican ancestry (Los Angeles)T;T 49%
  • Maasai (Kenya)T;T 61%
  • TuscanT;T 41%

Other DAO SNPs

All DAO SNPs

Notes

From SNPedia

Notes

Our findings suggest an influence of the gene in the neural substrate mediating sensorimotor gating and working memory, especially when combined with high anxiety. Genetic associations with schizophrenia: meta-analyses of 12 candidate genes. The neurobiology of D-amino acid oxidase and its involvement in schizophrenia. Persistence criteria for susceptibility genes for schizophrenia: a discussion from an evolutionary viewpoint.

Source and license

Adapted from rs4623951 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.