rs4624820

A SNP on chromosome 5. Its most notable genotype is A;A: increased testicular cancer risk for men

Gene
None listed
Location
Chr 5142,302,223 (GRCh38)
Highest magnitude
0.0Typical
Tested on
23andMe, AncestryDNA
Minor allele frequency
48%

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. A;AMost notableBadincreased testicular cancer risk for menTypical · 0.024% of people
  2. A;GBad1.37x increased testicular cancer risk for menTypical · 0.045% of people

On SNPedia: (A;A), (A;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 11 HapMap populations.

  • AverageA;A 24% A;G 45%
  • European ancestry (Utah)A;A 21% A;G 46%
  • Han Chinese (Beijing)A;A 7% A;G 37%
  • Japanese (Tokyo)A;A 8% A;G 40%
  • Yoruba (Nigeria)A;A 38% A;G 48%
  • African ancestry (Southwest US)A;A 35% A;G 46%
  • Chinese (Denver)A;A 7% A;G 41%
  • Gujarati IndianA;A 30% A;G 53%
  • Luhya (Kenya)A;A 30% A;G 47%
  • Mexican ancestry (Los Angeles)A;A 35% A;G 44%
  • Maasai (Kenya)A;A 17% A;G 53%
  • TuscanA;A 39% A;G 43%

Conditions, medicines and genes

Notes

From SNPedia

Notes

23andMe blog each rs4624820(A) increases the odds of testicular cancer by 1.37x

Source and license

Adapted from rs4624820 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.