rs4639334
A SNP in the LOC107987459 gene on chromosome 6. Its most notable genotype is A;A: Homozygous for HLA-DQ7 haplotype
- Gene
- LOC107987459
- Location
- Chr 632,634,437 (GRCh38)
- Highest magnitude
- 1.5Minor
- Tested on
- 23andMe
Genotypes
As shown in 23andMe and AncestryDNA files.
On SNPedia: (A;A), (A;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Frequency
Share of each genotype in 4 HapMap populations.
- AverageA;A 0% A;G 15%
- European ancestry (Utah)A;A 0% A;G 8%
- Han Chinese (Beijing)A;A 0% A;G 13%
- Japanese (Tokyo)A;A 0% A;G 11%
- Yoruba (Nigeria)A;A 0% A;G 29%
Notes
From SNPedia
Notes
rs4639334(A) is said to tag (i.e. identify the presence of) the HLA-DQ7 haplotype, at least in UK populations. Source nature Graves' disease or myasthenia gravis rs3129763(C) + rs4639334(C)
Source and license
Adapted from rs4639334 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.