rs4654748

A SNP in the NBPF3 gene on chromosome 1. Its most notable genotype is C;C: 2.90 ng/mL lower Vitamin B6 blood concentration

Gene
NBPF3
Location
Chr 121,459,575 (GRCh38)
Highest magnitude
2.0Worth knowing
Tested on
23andMe, AncestryDNA
Minor allele frequency
41%

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. C;CMost notableNot rated2.90 ng/mL lower Vitamin B6 blood concentrationWorth knowing · 2.044% of people
  2. C;TNot rated1.45 ng/mL lower Vitamin B6 blood concentrationWorth knowing · 2.040% of people
  3. T;TNot ratednormal Vitamin B6 blood concentrationTypical · 0.017% of people

On SNPedia: (C;C), (C;T), (T;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 11 HapMap populations.

  • AverageC;C 44% C;T 40% T;T 17%
  • European ancestry (Utah)C;C 34% C;T 47% T;T 20%
  • Han Chinese (Beijing)C;C 15% C;T 50% T;T 34%
  • Japanese (Tokyo)C;C 24% C;T 58% T;T 19%
  • Yoruba (Nigeria)C;C 87% C;T 13% T;T 0%
  • African ancestry (Southwest US)C;C 72% C;T 28% T;T 0%
  • Chinese (Denver)C;C 17% C;T 56% T;T 28%
  • Gujarati IndianC;C 39% C;T 49% T;T 13%
  • Luhya (Kenya)C;C 89% C;T 10% T;T <1%
  • Mexican ancestry (Los Angeles)C;C 29% C;T 35% T;T 36%
  • Maasai (Kenya)C;C 52% C;T 44% T;T 5%
  • TuscanC;C 22% C;T 51% T;T 28%

Notes

From SNPedia

Notes

This is one of the SNPs reported by NutraHacker. Genetics and genomics of human aging.

Source and license

Adapted from rs4654748 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.