rs4792311

A SNP in the ELAC2 gene on chromosome 17. Its most notable genotype is A;A: Increased risk of prostate cancer

Gene
ELAC2
Location
Chr 1713,011,692 (GRCh38)
Highest magnitude
2.0Worth knowing
Tested on
23andMe, AncestryDNA, FamilyTreeDNA
Minor allele frequency
21%

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. A;AMost notableBadIncreased risk of prostate cancerWorth knowing · 2.05% of people
  2. A;GBadIncreased risk of prostate cancerWorth knowing · 2.030% of people
  3. G;GGoodNormal risk of prostate cancerMinor · 1.065% of people

On SNPedia: (A;A), (A;G), (G;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 11 HapMap populations.

  • AverageA;A 5% A;G 30% G;G 65%
  • European ancestry (Utah)A;A 10% A;G 50% G;G 41%
  • Han Chinese (Beijing)A;A 0% A;G 6% G;G 94%
  • Japanese (Tokyo)A;A 0% A;G 4% G;G 97%
  • Yoruba (Nigeria)A;A 4% A;G 34% G;G 62%
  • African ancestry (Southwest US)A;A 2% A;G 39% G;G 60%
  • Chinese (Denver)A;A 0% A;G 7% G;G 93%
  • Gujarati IndianA;A 5% A;G 38% G;G 57%
  • Luhya (Kenya)A;A 6% A;G 36% G;G 58%
  • Mexican ancestry (Los Angeles)A;A 3% A;G 45% G;G 52%
  • Maasai (Kenya)A;A 12% A;G 40% G;G 48%
  • TuscanA;A 10% A;G 33% G;G 57%

Notes

From SNPedia

Notes

Sequence variants of elaC homolog 2 (Escherichia coli) (ELAC2) gene and susceptibility to prostate cancer in the Health Professionals Follow-Up Study. Development of a fingerprinting panel using medically relevant polymorphisms. Genetic variants and prostate cancer risk: candidate replication and exploration of viral restriction genes. Population based allele frequencies of disease associated polymorphisms in the Personalized Medicine Research Project.

Source and license

Adapted from rs4792311 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.