rs4833103

A SNP on chromosome 4. Its most notable genotype is A;A: normal

Gene
None listed
Location
Chr 438,813,881 (GRCh38)
Highest magnitude
0.0Typical
Tested on
23andMe, AncestryDNA, FamilyTreeDNA
Minor allele frequency
23%

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. A;AMost notableNot ratednormalTypical · 0.05% of people
  2. A;CNot rated0.75x decreased risk for Non-hodgkin's lymphomaTypical · 0.017% of people
  3. C;CNot rated0.74x decreased risk for Non-hodgkin's lymphomaTypical · 0.078% of people

On SNPedia: (A;A), (A;C), (C;C). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 9 HapMap populations.

  • AverageA;A 5% A;C 17% C;C 78%
  • European ancestry (Utah)A;A 31% A;C 48% C;C 21%
  • Han Chinese (Beijing)A;A 0% A;C 0% C;C 100%
  • Japanese (Tokyo)A;A 0% A;C 0% C;C 100%
  • Yoruba (Nigeria)A;A 0% A;C 0% C;C 100%
  • African ancestry (Southwest US)A;A 0% A;C 23% C;C 77%
  • Gujarati IndianA;A 0% A;C 4% C;C 96%
  • Mexican ancestry (Los Angeles)A;A 3% A;C 31% C;C 66%
  • Maasai (Kenya)A;A 0% A;C 1% C;C 99%
  • TuscanA;A 15% A;C 45% C;C 41%

Notes

From SNPedia

Notes

rs4833103 is a SNP located in a cluster of toll-like receptor genes. In a pooled analysis including three population-based case-control studies of Non-Hodgkin's lymphoma (1,946 cases, 1,808 controls), two SNPs in moderate linkage disequilibrium were significantly associated with NHL: rs10008492 (odds ratio for (C;T) genotype 1.12, CI: 0.97-1.30; OR(T;T) 1.40, CI: 1.15-1.71; p(trend)=0.001) and rs4833103 (OR(A;C) 0.75, CI: 0.64-0.88; OR(A;A) 0.74, CI: 0.62-0.90; p(trend)=0.002; p(dominant)=0.0002).

Source and license

Adapted from rs4833103 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.