rs4888378

A SNP in the CFDP1 gene on chromosome 16. Its most notable genotype is A;A: For women, slower carotid thickening with age (so presumably lower atherosclerotic risk)

Gene
CFDP1
Location
Chr 1675,298,143 (GRCh38)
Highest magnitude
2.4Worth knowing
Tested on
23andMe
Minor allele frequency
48%

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. A;AMost notableGoodFor women, slower carotid thickening with age (so presumably lower atherosclerotic risk)Worth knowing · 2.426% of people
  2. A;GGoodFor women, slower carotid thickening with age (so presumably lower atherosclerotic risk)Worth knowing · 2.247% of people

On SNPedia: (A;A), (A;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 11 HapMap populations.

  • AverageA;A 26% A;G 47%
  • European ancestry (Utah)A;A 13% A;G 55%
  • Han Chinese (Beijing)A;A 22% A;G 48%
  • Japanese (Tokyo)A;A 21% A;G 46%
  • Yoruba (Nigeria)A;A 46% A;G 50%
  • African ancestry (Southwest US)A;A 44% A;G 35%
  • Chinese (Denver)A;A 19% A;G 47%
  • Gujarati IndianA;A 23% A;G 52%
  • Luhya (Kenya)A;A 44% A;G 46%
  • Mexican ancestry (Los Angeles)A;A 12% A;G 31%
  • Maasai (Kenya)A;A 25% A;G 49%
  • TuscanA;A 20% A;G 57%

Notes

From SNPedia

Notes

A;A

See papers cited for rs4888378

A;G

See papers cited for rs4888378

Source and license

Adapted from rs4888378 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.