rs4919510

A SNP in the SEMA4G gene on chromosome 10. Its most notable genotype is C;C: common in complete genomics

Gene
SEMA4G
Location
Chr 10100,975,021 (GRCh38)
Highest magnitude
0.0Typical
Tested on
23andMe, AncestryDNA, FamilyTreeDNA
Minor allele frequency
35%

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. C;CMost notableGoodcommon in complete genomicsTypical · 0.037% of people

On SNPedia: (C;C). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 11 HapMap populations.

  • AverageC;C 37%
  • European ancestry (Utah)C;C 68%
  • Han Chinese (Beijing)C;C 18%
  • Japanese (Tokyo)C;C 18%
  • Yoruba (Nigeria)C;C 25%
  • African ancestry (Southwest US)C;C 29%
  • Chinese (Denver)C;C 21%
  • Gujarati IndianC;C 38%
  • Luhya (Kenya)C;C 29%
  • Mexican ancestry (Los Angeles)C;C 57%
  • Maasai (Kenya)C;C 35%
  • TuscanC;C 71%

Notes

From SNPedia

Notes

discussed in nature Single nucleotide polymorphisms of microRNA machinery genes modify the risk of renal cell carcinoma. Genetic variations in microRNA-related genes are novel susceptibility loci for esophageal cancer risk. Comprehensive analysis of the impact of SNPs and CNVs on human microRNAs and their regulatory genes. Genetic Polymorphisms in MicroRNA-Related Genes as Predictors of Clinical Outcomes in Colorectal Adenocarcinoma Patients.

Source and license

Adapted from rs4919510 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.