rs4954449

A SNP in the LCT gene on chromosome 2. Its most notable genotype is C;C: common in complete genomics

Gene
LCT
Location
Chr 2135,817,964 (GRCh38)
Highest magnitude
0.0Typical
Tested on
23andMe, FamilyTreeDNA
Minor allele frequency
2%

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. C;CMost notableGoodcommon in complete genomicsTypical · 0.092% of people
  2. T;TGoodcommon in clinvarTypical · 0.0<1% of people

On SNPedia: (C;C), (T;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 8 HapMap populations.

  • AverageC;C 92% T;T <1%
  • European ancestry (Utah)C;C 100% T;T 0%
  • Han Chinese (Beijing)C;C 100% T;T 0%
  • Japanese (Tokyo)C;C 100% T;T 0%
  • Yoruba (Nigeria)C;C 90% T;T <1%
  • African ancestry (Southwest US)C;C 83% T;T 0%
  • Luhya (Kenya)C;C 83% T;T <1%
  • Mexican ancestry (Los Angeles)C;C 98% T;T 0%
  • Maasai (Kenya)C;C 85% T;T 0%

Other LCT SNPs

All LCT SNPs

Source and license

Adapted from rs4954449 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.