rs4982731

A SNP in the CEBPE gene on chromosome 14. Its most notable genotype is C;C: Possible higher risk of childhood acute lymphoblastic leukemia

Gene
CEBPE
Location
Chr 1423,116,124 (GRCh38)
Highest magnitude
1.5Minor
Tested on
23andMe, AncestryDNA, FamilyTreeDNA
Minor allele frequency
30%

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. C;CMost notableBadPossible higher risk of childhood acute lymphoblastic leukemiaMinor · 1.512% of people
  2. T;TGoodnormalTypical · 0.045% of people

On SNPedia: (C;C), (T;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 11 HapMap populations.

  • AverageC;C 12% T;T 45%
  • European ancestry (Utah)C;C 9% T;T 42%
  • Han Chinese (Beijing)C;C 3% T;T 69%
  • Japanese (Tokyo)C;C 3% T;T 78%
  • Yoruba (Nigeria)C;C 17% T;T 33%
  • African ancestry (Southwest US)C;C 12% T;T 46%
  • Chinese (Denver)C;C 3% T;T 65%
  • Gujarati IndianC;C 12% T;T 37%
  • Luhya (Kenya)C;C 26% T;T 20%
  • Mexican ancestry (Los Angeles)C;C 12% T;T 31%
  • Maasai (Kenya)C;C 27% T;T 24%
  • TuscanC;C 6% T;T 47%

Other CEBPE SNPs

All CEBPE SNPs

Notes

From SNPedia

Notes

Novel susceptibility variants at 10p12.31-12.2 for childhood acute lymphoblastic leukemia in ethnically diverse populations.

Source and license

Adapted from rs4982731 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.