rs499697

A SNP on chromosome 1. Its most notable genotype is A;A: straighter hair

Gene
None listed
Location
Chr 1152,520,678 (GRCh38)
Highest magnitude
2.0Worth knowing
Tested on
23andMe, AncestryDNA, FamilyTreeDNA
Minor allele frequency
20%

Genotypes

Plus strand, as in 23andMe and AncestryDNA files.

  1. A;AMost notableNot ratedstraighter hairWorth knowing · 2.071% of people

SNPedia records rs499697 on the minus strand: (T;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 11 HapMap populations.

  • AverageA;A 71%
  • European ancestry (Utah)A;A 53%
  • Han Chinese (Beijing)A;A 58%
  • Japanese (Tokyo)A;A 57%
  • Yoruba (Nigeria)A;A 98%
  • African ancestry (Southwest US)A;A 90%
  • Chinese (Denver)A;A 62%
  • Gujarati IndianA;A 58%
  • Luhya (Kenya)A;A 99%
  • Mexican ancestry (Los Angeles)A;A 63%
  • Maasai (Kenya)A;A 89%
  • TuscanA;A 55%

Notes

From SNPedia

Notes

rs499697 the minor, derived allele is associated with curlier hair curl, 0.13 points per G.

Source and license

Adapted from rs499697 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.