rs5009270

A SNP on chromosome 7. Its most notable genotype is A;A: possible risk of osteoarthritis of the hip.

Gene
None listed
Location
Chr 7112,519,123 (GRCh38)
Highest magnitude
1.1Minor
Tested on
23andMe, AncestryDNA, FamilyTreeDNA

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. A;AMost notableBadpossible risk of osteoarthritis of the hip.Minor · 1.115% of people

On SNPedia: (A;A). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 11 HapMap populations.

  • AverageA;A 15%
  • European ancestry (Utah)A;A 12%
  • Han Chinese (Beijing)A;A <1%
  • Japanese (Tokyo)A;A 0%
  • Yoruba (Nigeria)A;A 31%
  • African ancestry (Southwest US)A;A 25%
  • Chinese (Denver)A;A 2%
  • Gujarati IndianA;A 14%
  • Luhya (Kenya)A;A 23%
  • Mexican ancestry (Los Angeles)A;A 5%
  • Maasai (Kenya)A;A 33%
  • TuscanA;A 21%

Notes

From SNPedia

Notes

2014 study of 11,277 cases of radiographic and symptomatic hip OA. Suggestive association of 1.1x OD for rs5009270

A;A

Based on suggestive connection of 1.1x risk for A allele, possibly more impact for homozygous AA. See text at rs5009270

Source and license

Adapted from rs5009270 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.