rs5030737

A SNP in the MBL2 gene on chromosome 10. Its most notable genotype is A;A: mannose binding deficiency but of low clinical importance

Gene
MBL2
Location
Chr 1052,771,482 (GRCh38)
Highest magnitude
1.6Minor
Tested on
23andMe, AncestryDNA, FamilyTreeDNA
Minor allele frequency
3%

Genotypes

Plus strand, as in 23andMe and AncestryDNA files.

  1. G;GGoodcommon in clinvarTypical · 0.094% of people
  2. A;GBadcarrier of mannose binding deficiency but of low clinical importanceMinor · 1.16% of people
  3. A;AMost notableBadmannose binding deficiency but of low clinical importanceMinor · 1.60% of people

SNPedia records rs5030737 on the minus strand: (C;C), (C;T), (T;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 10 HapMap populations.

  • AverageG;G 94% A;G 6% A;A 0%
  • European ancestry (Utah)G;G 86% A;G 14% A;A 0%
  • Han Chinese (Beijing)G;G 99% A;G 2% A;A 0%
  • Japanese (Tokyo)G;G 98% A;G 2% A;A 0%
  • Yoruba (Nigeria)G;G 99% A;G <1% A;A 0%
  • African ancestry (Southwest US)G;G 98% A;G 2% A;A 0%
  • Gujarati IndianG;G 93% A;G 7% A;A 0%
  • Luhya (Kenya)G;G 96% A;G 4% A;A 0%
  • Mexican ancestry (Los Angeles)G;G 96% A;G 4% A;A 0%
  • Maasai (Kenya)G;G 89% A;G 11% A;A 0%
  • TuscanG;G 90% A;G 10% A;A 0%

Other MBL2 SNPs

All MBL2 SNPs

Source and license

Adapted from rs5030737 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.