rs5110

A SNP in the APOA4 gene on chromosome 11. Its most notable genotype is C;C: common in clinvar

Gene
APOA4
Location
Chr 11116,820,918 (GRCh38)
Highest magnitude
0.0Typical
Tested on
23andMe, AncestryDNA, FamilyTreeDNA
Minor allele frequency
3%

Genotypes

Plus strand, as in 23andMe and AncestryDNA files.

  1. C;CMost notableGoodcommon in clinvarTypical · 0.095% of people

SNPedia records rs5110 on the minus strand: (G;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 10 HapMap populations.

  • AverageC;C 95%
  • European ancestry (Utah)C;C 81%
  • Han Chinese (Beijing)C;C 99%
  • Japanese (Tokyo)C;C 97%
  • Yoruba (Nigeria)C;C 99%
  • African ancestry (Southwest US)C;C 98%
  • Chinese (Denver)C;C 99%
  • Gujarati IndianC;C 98%
  • Luhya (Kenya)C;C 96%
  • Mexican ancestry (Los Angeles)C;C 93%
  • TuscanC;C 90%

Notes

From SNPedia

Notes

The apolipoprotein A-IV polymorphism rs5110 is also known as c.1140G>T, p.Gln380His and Q360H.

Source and license

Adapted from rs5110 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.