rs5182
A SNP in the AGTR1 gene on chromosome 3. Its most notable genotype is C;C: common in clinvar
- Gene
- AGTR1
- Location
- Chr 3148,741,608 (GRCh38)
- Highest magnitude
- 0.0Typical
- Tested on
- 23andMe, AncestryDNA, FamilyTreeDNA
- Minor allele frequency
- 47%
Genotypes
As shown in 23andMe and AncestryDNA files.
On SNPedia: (C;C). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Frequency
Share of each genotype in 4 HapMap populations.
- AverageC;C 32%
- European ancestry (Utah)C;C 25%
- Han Chinese (Beijing)C;C 22%
- Japanese (Tokyo)C;C 9%
- Yoruba (Nigeria)C;C 71%
Related
Conditions, medicines and genes
Notes
From SNPedia
Notes
rs5182 (573C/T) is a SNP within the AGTR1 (Angiotensin II receptor type 1). among 4,096 hypertensive subjects, the CT/CC genotypes were associated with reduced risk of heart attack among those treated with ACE inhibitors
Source and license
Adapted from rs5182 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.