rs5400

A SNP in the SLC2A2 gene on chromosome 3. Its most notable genotype is A;A: significantly higher sugar consumption

Gene
SLC2A2
Location
Chr 3171,014,511 (GRCh38)
Highest magnitude
1.8Minor
Tested on
23andMe, AncestryDNA, FamilyTreeDNA
Minor allele frequency
19%

Genotypes

Plus strand, as in 23andMe and AncestryDNA files.

  1. G;GNot ratednormal sugar consumptionTypical · 0.163% of people
  2. A;GNot ratedsignificantly higher sugar consumption?Minor · 1.729% of people
  3. A;AMost notableNot ratedsignificantly higher sugar consumptionMinor · 1.88% of people

SNPedia records rs5400 on the minus strand: (C;C), (C;T), (T;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 11 HapMap populations.

  • AverageG;G 63% A;G 29% A;A 8%
  • European ancestry (Utah)G;G 76% A;G 19% A;A 5%
  • Han Chinese (Beijing)G;G 96% A;G 4% A;A 0%
  • Japanese (Tokyo)G;G 95% A;G 5% A;A 0%
  • Yoruba (Nigeria)G;G 20% A;G 54% A;A 26%
  • African ancestry (Southwest US)G;G 37% A;G 47% A;A 16%
  • Chinese (Denver)G;G 98% A;G 2% A;A 0%
  • Gujarati IndianG;G 68% A;G 25% A;A 7%
  • Luhya (Kenya)G;G 26% A;G 56% A;A 18%
  • Mexican ancestry (Los Angeles)G;G 62% A;G 33% A;A 5%
  • Maasai (Kenya)G;G 42% A;G 46% A;A 12%
  • TuscanG;G 73% A;G 25% A;A 3%

Notes

From SNPedia

Notes

rs5400(T;T) carriers had a significantly higher intake of sugars blog discussion Food Preference

Source and license

Adapted from rs5400 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.