rs5522

A SNP in the NR3C2 gene on chromosome 4. Its most notable genotype is T;T: common on affy axiom data

Gene
NR3C2
Location
Chr 4148,436,323 (GRCh38)
Highest magnitude
0.0Typical
Tested on
23andMe, AncestryDNA, FamilyTreeDNA
Minor allele frequency
12%

Genotypes

Plus strand, as in 23andMe and AncestryDNA files.

  1. T;TMost notableGoodcommon on affy axiom dataTypical · 0.079% of people
  2. C;CGoodcommon in clinvarTypical · 0.02% of people
  3. A;ANot ratedNo summary available.Typical · 0.00% of people

SNPedia records rs5522 on the minus strand: (A;A), (G;G), (T;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 11 HapMap populations.

  • AverageT;T 79% C;C 2% A;A 0%
  • European ancestry (Utah)T;T 81% C;C <1% A;A 0%
  • Han Chinese (Beijing)T;T 73% C;C 3% A;A 0%
  • Japanese (Tokyo)T;T 64% C;C 7% A;A 0%
  • Yoruba (Nigeria)T;T 83% C;C <1% A;A 0%
  • African ancestry (Southwest US)T;T 93% C;C 2% A;A 0%
  • Chinese (Denver)T;T 77% C;C 2% A;A 0%
  • Gujarati IndianT;T 86% C;C 0% A;A 0%
  • Luhya (Kenya)T;T 82% C;C 0% A;A 0%
  • Mexican ancestry (Los Angeles)T;T 71% C;C 2% A;A 0%
  • Maasai (Kenya)T;T 72% C;C 1% A;A 0%
  • TuscanT;T 86% C;C 0% A;A 0%

Other NR3C2 SNPs

All NR3C2 SNPs

Source and license

Adapted from rs5522 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.