rs572169

A SNP in the GHSR gene on chromosome 3. Its most notable genotype is C;C: common in clinvar

Gene
GHSR
Location
Chr 3172,447,937 (GRCh38)
Highest magnitude
0.0Typical
Tested on
23andMe, AncestryDNA, FamilyTreeDNA
Minor allele frequency
27%

Genotypes

Plus strand, as in 23andMe and AncestryDNA files.

  1. C;CMost notableGoodcommon in clinvarTypical · 0.061% of people

SNPedia records rs572169 on the minus strand: (G;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 11 HapMap populations.

  • AverageC;C 61%
  • European ancestry (Utah)C;C 49%
  • Han Chinese (Beijing)C;C 33%
  • Japanese (Tokyo)C;C 36%
  • Yoruba (Nigeria)C;C 92%
  • African ancestry (Southwest US)C;C 88%
  • Chinese (Denver)C;C 34%
  • Gujarati IndianC;C 66%
  • Luhya (Kenya)C;C 89%
  • Mexican ancestry (Los Angeles)C;C 45%
  • Maasai (Kenya)C;C 80%
  • TuscanC;C 60%

Other GHSR SNPs

All GHSR SNPs

Notes

From SNPedia

Show notes, about 130 words

Ghrelin receptor gene polymorphisms and body size in children and adults. Association studies on ghrelin and ghrelin receptor gene polymorphisms with obesity. Association of maternally inherited GNAS alleles with African-American male birth weight. Family and population-based studies of variation within the ghrelin receptor locus in relation to measures of obesity. Genetic variation of the ghrelin signaling system in females with severe alcohol dependence. The ghrelin signalling system is involved in the consumption of sweets. Human longevity and variation in GH/IGF-1/insulin signaling, DNA damage signaling and repair and pro/antioxidant pathway genes: cross sectional and longitudinal studies. GH secretagogue receptor gene polymorphisms are associated with stature throughout childhood.

Source and license

Adapted from rs572169 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.