rs5742913

A SNP in the TCF7 gene on chromosome 5. Its most notable genotype is C;C.

Gene
TCF7
Location
Chr 5134,115,992 (GRCh38)
Highest magnitude
0.0Typical
Tested on
23andMe
Minor allele frequency
5%

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. C;CMost notableNot ratedNo summary available.Typical · 0.090% of people

On SNPedia: (C;C). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 10 HapMap populations.

  • AverageC;C 90%
  • European ancestry (Utah)C;C 75%
  • Han Chinese (Beijing)C;C 99%
  • Japanese (Tokyo)C;C 100%
  • Yoruba (Nigeria)C;C 100%
  • African ancestry (Southwest US)C;C 93%
  • Gujarati IndianC;C 96%
  • Luhya (Kenya)C;C 97%
  • Mexican ancestry (Los Angeles)C;C 76%
  • Maasai (Kenya)C;C 90%
  • TuscanC;C 74%

Other TCF7 SNPs

All TCF7 SNPs

Notes

From SNPedia

Show notes, about 140 words

Gene-environment interaction effects on the development of immune responses in the 1st year of life. The candidate genes TAF5L, TCF7, PDCD1, IL6 and ICAM1 cannot be excluded from having effects in type 1 diabetes. A meta-analysis of candidate gene polymorphisms and ischemic stroke in 6 study populations: association of lymphotoxin-alpha in nonhypertensive patients. Genetic risk factors in recurrent venous thromboembolism: A multilocus, population-based, prospective approach. Association of 77 polymorphisms in 52 candidate genes with blood pressure progression and incident hypertension: the Women's Genome Health Study. A candidate gene association study of 77 polymorphisms in migraine. Overview of the Rapid Response data. The Type I Diabetes Genetics Consortium 'Rapid Response' family-based candidate gene study: strategy, genes selection, and main outcome.

Source and license

Adapted from rs5742913 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.