rs5750285
A SNP in the LOC105373021 gene on chromosome 22. Its most notable genotype is C;C: Better response to lithium treatment
- Gene
- LOC105373021
- Location
- Chr 2236,708,203 (GRCh38)
- Highest magnitude
- 0.0Typical
- Tested on
- 23andMe
- Minor allele frequency
- 49%
Genotypes
As shown in 23andMe and AncestryDNA files.
On SNPedia: (C;C), (C;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Frequency
Share of each genotype in 4 HapMap populations.
- AverageC;C 22% C;G 47%
- European ancestry (Utah)C;C 35% C;G 52%
- Han Chinese (Beijing)C;C 31% C;G 42%
- Japanese (Tokyo)C;C 16% C;G 46%
- Yoruba (Nigeria)C;C 6% C;G 46%
Notes
From SNPedia
Notes
PMID 18408563 Stargazin involvement with bipolar disorder and response to lithium treatment.
Source and license
Adapted from rs5750285 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.