rs5968255

A SNP on chromosome X. Its most notable genotype is C;C: slower AIDS progression (8 years)

Gene
None listed
Location
Chr X83,999,684 (GRCh38)
Highest magnitude
1.5Minor
Tested on
23andMe, AncestryDNA
Minor allele frequency
21%

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. C;CMost notableGoodslower AIDS progression (8 years)Minor · 1.513% of people
  2. T;TBadcommon, but faster HIV progressionTypical · 0.077% of people

On SNPedia: (C;C), (T;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 8 HapMap populations.

  • AverageC;C 13% T;T 77%
  • European ancestry (Utah)C;C 8% T;T 79%
  • Han Chinese (Beijing)C;C 36% T;T 42%
  • Japanese (Tokyo)C;C 48% T;T 32%
  • Yoruba (Nigeria)C;C 2% T;T 95%
  • African ancestry (Southwest US)C;C 2% T;T 89%
  • Luhya (Kenya)C;C 4% T;T 92%
  • Maasai (Kenya)C;C 5% T;T 90%
  • TuscanC;C 2% T;T 96%

Conditions, medicines and genes

Genosets

Genosets combine several genotypes. Twofold checks them in your report.

Notes

From SNPedia

Notes

23andMe blog females with one copy of rs5968255(C) progressed from HIV infection to AIDS more slowly with an average of eight years, nearly four times more than females with no copies or males. The search for host genetic factors of HIV/AIDS pathogenesis in the post-genome era: progress to date and new avenues for discovery. Genome-wide association study SNPs in the human genome diversity project populations: does selection affect unlinked SNPs with shared trait associations? HIV Progression

Source and license

Adapted from rs5968255 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.