rs5993891

A SNP in the ARVCF gene on chromosome 22. Its most notable genotype is C;C: common in complete genomics

Gene
ARVCF
Location
Chr 2219,972,223 (GRCh38)
Highest magnitude
0.0Typical
Tested on
23andMe, FamilyTreeDNA
Minor allele frequency
13%

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. C;CMost notableGoodcommon in complete genomicsTypical · 0.070% of people

On SNPedia: (C;C). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 11 HapMap populations.

  • AverageC;C 70%
  • European ancestry (Utah)C;C 86%
  • Han Chinese (Beijing)C;C 94%
  • Japanese (Tokyo)C;C 94%
  • Yoruba (Nigeria)C;C 36%
  • African ancestry (Southwest US)C;C 40%
  • Chinese (Denver)C;C 91%
  • Gujarati IndianC;C 76%
  • Luhya (Kenya)C;C 36%
  • Mexican ancestry (Los Angeles)C;C 81%
  • Maasai (Kenya)C;C 51%
  • TuscanC;C 90%

Conditions, medicines and genes

Other ARVCF SNPs

All ARVCF SNPs

Genosets

Genosets combine several genotypes. Twofold checks them in your report.

Notes

From SNPedia

Notes

rs5993891 is a SNP in the armadillo repeat gene deleted in velocardiofacial syndrome ARVCF gene - how's that for a gene name? This SNP is one of five SNPs reported to be useful in a SNP set defining the risk of dying from prostate cancer among patients with the disease; see gs242 and gs243.

Source and license

Adapted from rs5993891 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.