rs6013029

A SNP in the CTNNBL1 gene on chromosome 20. Its most notable genotype is G;G: normal

Gene
CTNNBL1
Location
Chr 2037,771,178 (GRCh38)
Highest magnitude
0.0Typical
Tested on
23andMe, AncestryDNA, FamilyTreeDNA
Minor allele frequency
9%

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. G;GMost notableGoodnormalTypical · 0.082% of people
  2. G;TNot ratedNo summary available.Typical · 0.016% of people
  3. T;TNot ratedNo summary available.Typical · 0.01% of people

On SNPedia: (G;G), (G;T), (T;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 11 HapMap populations.

  • AverageG;G 82% G;T 16% T;T 1%
  • European ancestry (Utah)G;G 92% G;T 7% T;T <1%
  • Han Chinese (Beijing)G;G 99% G;T <1% T;T 0%
  • Japanese (Tokyo)G;G 98% G;T 2% T;T 0%
  • Yoruba (Nigeria)G;G 50% G;T 44% T;T 5%
  • African ancestry (Southwest US)G;G 61% G;T 37% T;T 2%
  • Chinese (Denver)G;G 97% G;T 3% T;T 0%
  • Gujarati IndianG;G 96% G;T 4% T;T 0%
  • Luhya (Kenya)G;G 66% G;T 30% T;T 5%
  • Mexican ancestry (Los Angeles)G;G 91% G;T 9% T;T 0%
  • Maasai (Kenya)G;G 63% G;T 35% T;T 3%
  • TuscanG;G 91% G;T 8% T;T 1%

Conditions, medicines and genes

Notes

From SNPedia

Show notes, about 130 words

rs6013029 is a SNP in the CTNNBL1 gene. Found no evidence of early onset obesity or increased body mass index association with this SNP in several populations (~3,000 cases overall) of Central European (German) ancestry. While the older a study of ~1,900 Caucasians turned up associations between several SNPs in the CTNNBL1 gene and increased risk for obesity, of which rs6013029 was statistically the strongest, with an odds ratio of 1.42 for (T;T) homozgyotes compared to (G;G) homozygotes. This SNP achieved experiment-wise p values of 2.69 x 10 -7 for body mass index (BMI) and of 4.99 x 10 -8 for fat mass, respectively. The rs6013029(T) allele confers an average increase in BMI and fat mass of 2.67 kg/m(2) and 5.96 kg, respectively, compared to rs6013029(G).

Source and license

Adapted from rs6013029 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.