rs6046

A SNP in the F7 gene on chromosome 13. Its most notable genotype is A;A: better blood pressure, lower risk of myocardial infarction

Gene
F7
Location
Chr 13113,118,845 (GRCh38)
Highest magnitude
2.8Worth knowing
Tested on
23andMe, AncestryDNA, FamilyTreeDNA
Minor allele frequency
9%

Genotypes

Plus strand, as in 23andMe and AncestryDNA files.

  1. G;GBadcommon in clinvarTypical · 0.075% of people
  2. A;AMost notableGoodbetter blood pressure, lower risk of myocardial infarctionWorth knowing · 2.82% of people

SNPedia records rs6046 on the minus strand: (C;C), (T;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 11 HapMap populations.

  • AverageG;G 75% A;A 2%
  • European ancestry (Utah)G;G 78% A;A 3%
  • Han Chinese (Beijing)G;G 84% A;A 0%
  • Japanese (Tokyo)G;G 86% A;A <1%
  • Yoruba (Nigeria)G;G 75% A;A 0%
  • African ancestry (Southwest US)G;G 89% A;A 2%
  • Chinese (Denver)G;G 94% A;A 0%
  • Gujarati IndianG;G 51% A;A 3%
  • Luhya (Kenya)G;G 71% A;A 2%
  • Mexican ancestry (Los Angeles)G;G 69% A;A 2%
  • Maasai (Kenya)G;G 58% A;A 3%
  • TuscanG;G 68% A;A 5%

Other F7 SNPs

All F7 SNPs

Genosets

Genosets combine several genotypes. Twofold checks them in your report.

Notes

From SNPedia

Notes

G;G

you have the common genotype, but rare genotype has a beneficial effect on blood pressure and risk of myocardial infarction.

Source and license

Adapted from rs6046 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.