rs6060369

A SNP in the UQCC gene on chromosome 20. Its most notable genotype is A;G.

Gene
UQCC
Location
Chr 2035,319,358 (GRCh38)
Highest magnitude
2.0Worth knowing
Tested on
23andMe, AncestryDNA
Minor allele frequency
43%

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. A;ANot ratedNo summary available.Typical · 0.00% of people
  2. A;GMost notableNot ratedNo summary available.Worth knowing · 2.00% of people
  3. C;CNot rated0.88cm tallerTypical · 0.032% of people
  4. C;TNot rated0.44cm tallerTypical · 0.037% of people
  5. T;TNot ratednormal heightTypical · 0.032% of people

On SNPedia: (A;A), (A;G), (C;C), (C;T), (T;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 11 HapMap populations.

  • AverageA;A 0% A;G 0% C;C 32% C;T 37% T;T 32%
  • European ancestry (Utah)A;A 0% A;G 0% C;C 12% C;T 43% T;T 45%
  • Han Chinese (Beijing)A;A 0% A;G 0% C;C 6% C;T 39% T;T 55%
  • Japanese (Tokyo)A;A 0% A;G 0% C;C 10% C;T 32% T;T 58%
  • Yoruba (Nigeria)A;A 0% A;G 0% C;C 63% C;T 30% T;T 7%
  • African ancestry (Southwest US)A;A 0% A;G 0% C;C 44% C;T 44% T;T 12%
  • Chinese (Denver)A;A 0% A;G 0% C;C 9% C;T 34% T;T 57%
  • Gujarati IndianA;A 0% A;G 0% C;C 46% C;T 44% T;T 11%
  • Luhya (Kenya)A;A 0% A;G 0% C;C 72% C;T 26% T;T 3%
  • Mexican ancestry (Los Angeles)A;A 0% A;G 0% C;C 10% C;T 26% T;T 64%
  • Maasai (Kenya)A;A 0% A;G 0% C;C 56% C;T 37% T;T 8%
  • TuscanA;A 0% A;G 0% C;C 22% C;T 51% T;T 28%

Conditions, medicines and genes

Notes

From SNPedia

Show notes, about 120 words

rs6060369 is a SNP associated with a (slight) increase in height, in that individuals tend to be 0.44cm taller for each rs6060369(C) allele they carry. This finding was statistically significant (p=9.7x10e-7), and ultimately tested in over 28,000 individuals. A haplotype of rs6060369 and rs143383, a neighboring SNP in the GDF5 gene, can be defined, which also links height to osteoarthritis since rs143383 has previously been linked to osteoarthritis. Medpage article Genome-wide association scan for stature in Chinese: evidence for ethnic specific loci. Genome-wide association studies in an isolated founder population from the Pacific Island of Kosrae. Assessing the impact of global versus local ancestry in association studies.

Source and license

Adapted from rs6060369 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.