rs629242

A SNP in the KIAA1211 gene on chromosome 4. Its most notable genotype is T;T: somewhat higher risk for prostate cancer

Gene
KIAA1211
Location
Chr 456,276,871 (GRCh38)
Highest magnitude
2.1Worth knowing
Tested on
23andMe, AncestryDNA, FamilyTreeDNA
Minor allele frequency
26%

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. C;CGoodnormal riskTypical · 0.055% of people
  2. C;TBadsomewhat higher risk for prostate cancerWorth knowing · 2.037% of people
  3. T;TMost notableBadsomewhat higher risk for prostate cancerWorth knowing · 2.18% of people

On SNPedia: (C;C), (C;T), (T;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 11 HapMap populations.

  • AverageC;C 55% C;T 37% T;T 8%
  • European ancestry (Utah)C;C 66% C;T 31% T;T 4%
  • Han Chinese (Beijing)C;C 43% C;T 46% T;T 11%
  • Japanese (Tokyo)C;C 49% C;T 42% T;T 9%
  • Yoruba (Nigeria)C;C 40% C;T 46% T;T 14%
  • African ancestry (Southwest US)C;C 33% C;T 49% T;T 18%
  • Chinese (Denver)C;C 42% C;T 44% T;T 14%
  • Gujarati IndianC;C 68% C;T 30% T;T 2%
  • Luhya (Kenya)C;C 61% C;T 35% T;T 4%
  • Mexican ancestry (Los Angeles)C;C 78% C;T 21% T;T 2%
  • Maasai (Kenya)C;C 69% C;T 27% T;T 5%
  • TuscanC;C 58% C;T 35% T;T 7%

Conditions, medicines and genes

Notes

From SNPedia

Notes

rs629242 is one of seven SNPs found in a combined study of over 1,000 patients to be associated with increased risk for prostate cancer. The risk allele for this SNP is (T); and while the odds ratio was not specifically reported, the probability of false significance (not permuted though) was given as p=7.2 x 10e-7, using an additive model of risk.

Source and license

Adapted from rs629242 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.