rs6532197

A SNP on chromosome 4. Its most notable genotype is G;G: Increased risk of developing Parkinson's Disease

Gene
None listed
Location
Chr 489,876,150 (GRCh38)
Highest magnitude
2.0Worth knowing
Tested on
23andMe, AncestryDNA
Minor allele frequency
20%

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. A;AGoodNormal risk of developing Parkinson's DiseaseMinor · 1.059% of people
  2. A;GBadSlightly increased risk of developing Parkinson's DiseaseMinor · 1.534% of people
  3. G;GMost notableBadIncreased risk of developing Parkinson's DiseaseWorth knowing · 2.07% of people

On SNPedia: (A;A), (A;G), (G;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 11 HapMap populations.

  • AverageA;A 59% A;G 34% G;G 7%
  • European ancestry (Utah)A;A 84% A;G 15% G;G <1%
  • Han Chinese (Beijing)A;A 54% A;G 40% G;G 7%
  • Japanese (Tokyo)A;A 48% A;G 43% G;G 10%
  • Yoruba (Nigeria)A;A 37% A;G 52% G;G 11%
  • African ancestry (Southwest US)A;A 44% A;G 44% G;G 12%
  • Chinese (Denver)A;A 40% A;G 53% G;G 7%
  • Gujarati IndianA;A 86% A;G 13% G;G 1%
  • Luhya (Kenya)A;A 44% A;G 43% G;G 13%
  • Mexican ancestry (Los Angeles)A;A 88% A;G 9% G;G 3%
  • Maasai (Kenya)A;A 37% A;G 49% G;G 14%
  • TuscanA;A 81% A;G 18% G;G 1%

Source and license

Adapted from rs6532197 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.