rs6587852
A SNP on chromosome 1. Its most notable genotype is C;C.
- Gene
- None listed
- Location
- Chr 159,239,775 (GRCh38)
- Highest magnitude
- 0.0Typical
- Tested on
- 23andMe, AncestryDNA, FamilyTreeDNA
- Minor allele frequency
- 23%
Genotypes
As shown in 23andMe and AncestryDNA files.
On SNPedia: (C;C). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Frequency
Share of each genotype in 11 HapMap populations.
- AverageC;C 59%
- European ancestry (Utah)C;C 65%
- Han Chinese (Beijing)C;C 79%
- Japanese (Tokyo)C;C 61%
- Yoruba (Nigeria)C;C 40%
- African ancestry (Southwest US)C;C 60%
- Chinese (Denver)C;C 65%
- Gujarati IndianC;C 58%
- Luhya (Kenya)C;C 38%
- Mexican ancestry (Los Angeles)C;C 85%
- Maasai (Kenya)C;C 41%
- TuscanC;C 55%
Notes
From SNPedia
Notes
rs6587852 is one of 6 SNPs found upstream of an (uncharacterized) gene known as FLJ10986 that have been found to be overrepresented in 1,152 patients with sporadic amyotrophic lateral sclerosis (ALS). A study involving a large case-control series from the Netherlands, Belgium, Sweden and Ireland (total: 1883 sporadic ALS patients and 2063 controls) found no significant association between sporadic ALS and the six previously reported associated SNPs, including this one.
Source and license
Adapted from rs6587852 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.