rs6590357

A SNP in the C11orf45 gene on chromosome 11. Its most notable genotype is C;C: common in complete genomics

Gene
C11orf45
Location
Chr 11128,911,444 (GRCh38)
Highest magnitude
0.0Typical
Tested on
23andMe, AncestryDNA
Minor allele frequency
15%

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. C;CMost notableGoodcommon in complete genomicsTypical · 0.075% of people
  2. T;TGoodcommon in clinvarTypical · 0.02% of people

On SNPedia: (C;C), (T;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 11 HapMap populations.

  • AverageC;C 75% T;T 2%
  • European ancestry (Utah)C;C 67% T;T 3%
  • Han Chinese (Beijing)C;C 80% T;T <1%
  • Japanese (Tokyo)C;C 72% T;T 2%
  • Yoruba (Nigeria)C;C 80% T;T <1%
  • African ancestry (Southwest US)C;C 68% T;T 2%
  • Chinese (Denver)C;C 82% T;T <1%
  • Gujarati IndianC;C 77% T;T 3%
  • Luhya (Kenya)C;C 73% T;T <1%
  • Mexican ancestry (Los Angeles)C;C 64% T;T 3%
  • Maasai (Kenya)C;C 87% T;T <1%
  • TuscanC;C 78% T;T 2%

Source and license

Adapted from rs6590357 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.