rs6601764

A SNP on chromosome 10. Its most notable genotype is C;C: 1.52x increased risk of developing Crohn's disease

Gene
None listed
Location
Chr 103,820,350 (GRCh38)
Highest magnitude
2.0Worth knowing
Tested on
23andMe, AncestryDNA
Minor allele frequency
37%

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. C;CMost notableBad1.52x increased risk of developing Crohn's diseaseWorth knowing · 2.045% of people
  2. C;TBad1.16x increased risk of developing Crohn's diseaseMinor · 1.544% of people
  3. T;TGoodNormal risk of developing Crohn's diseaseMinor · 1.011% of people

On SNPedia: (C;C), (C;T), (T;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 11 HapMap populations.

  • AverageC;C 45% C;T 44% T;T 11%
  • European ancestry (Utah)C;C 19% C;T 55% T;T 27%
  • Han Chinese (Beijing)C;C 61% C;T 36% T;T 4%
  • Japanese (Tokyo)C;C 50% C;T 40% T;T 10%
  • Yoruba (Nigeria)C;C 64% C;T 33% T;T 3%
  • African ancestry (Southwest US)C;C 44% C;T 47% T;T 9%
  • Chinese (Denver)C;C 62% C;T 36% T;T 2%
  • Gujarati IndianC;C 44% C;T 46% T;T 11%
  • Luhya (Kenya)C;C 53% C;T 42% T;T 6%
  • Mexican ancestry (Los Angeles)C;C 36% C;T 50% T;T 14%
  • Maasai (Kenya)C;C 47% C;T 42% T;T 12%
  • TuscanC;C 18% C;T 55% T;T 28%

Conditions, medicines and genes

Notes

From SNPedia

Notes

rs6601764 has been reported in a large study to be associated with Crohn's disease. The risk allele (oriented to the dbSNP entry) is (C); the odds ratio associated with heterozygotes is 1.16 (CI 1.01-1.33), and for homozygotes, 1.52 (CI 1.28-1.80).

Source and license

Adapted from rs6601764 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.