rs6675281

A SNP in the DISC2 gene on chromosome 1. Its most notable genotype is C;C: common

Gene
DISC2
Location
Chr 1231,818,355 (GRCh38)
Highest magnitude
0.0Typical
Tested on
23andMe, AncestryDNA, FamilyTreeDNA
Minor allele frequency
9%

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. C;CMost notableGoodcommonTypical · 0.085% of people
  2. C;TNot ratedNo summary available.Typical · 0.014% of people
  3. T;TNot ratedNo summary available.Typical · 0.01% of people

On SNPedia: (C;C), (C;T), (T;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 11 HapMap populations.

  • AverageC;C 85% C;T 14% T;T 1%
  • European ancestry (Utah)C;C 70% C;T 28% T;T 2%
  • Han Chinese (Beijing)C;C 100% C;T 0% T;T 0%
  • Japanese (Tokyo)C;C 100% C;T 0% T;T 0%
  • Yoruba (Nigeria)C;C 70% C;T 25% T;T 5%
  • African ancestry (Southwest US)C;C 81% C;T 18% T;T 2%
  • Chinese (Denver)C;C 99% C;T <1% T;T 0%
  • Gujarati IndianC;C 96% C;T 4% T;T 0%
  • Luhya (Kenya)C;C 67% C;T 27% T;T 6%
  • Mexican ancestry (Los Angeles)C;C 88% C;T 12% T;T 0%
  • Maasai (Kenya)C;C 83% C;T 17% T;T 0%
  • TuscanC;C 80% C;T 18% T;T 2%

Conditions, medicines and genes

Notes

From SNPedia

Notes

linked to schizophrenia

Source and license

Adapted from rs6675281 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.