rs667773

A SNP in the PAX6 gene on chromosome 11. Its most notable genotype is G;G: common in clinvar

Gene
PAX6
Location
Chr 1131,793,814 (GRCh38)
Highest magnitude
0.0Typical
Tested on
23andMe
Minor allele frequency
9%

Genotypes

Plus strand, as in 23andMe and AncestryDNA files.

  1. G;GMost notableGoodcommon in clinvarTypical · 0.081% of people

SNPedia records rs667773 on the minus strand: (C;C). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 11 HapMap populations.

  • AverageG;G 81%
  • European ancestry (Utah)G;G 90%
  • Han Chinese (Beijing)G;G 68%
  • Japanese (Tokyo)G;G 78%
  • Yoruba (Nigeria)G;G 93%
  • African ancestry (Southwest US)G;G 89%
  • Chinese (Denver)G;G 63%
  • Gujarati IndianG;G 91%
  • Luhya (Kenya)G;G 86%
  • Mexican ancestry (Los Angeles)G;G 66%
  • Maasai (Kenya)G;G 74%
  • TuscanG;G 88%

Other PAX6 SNPs

All PAX6 SNPs

Notes

From SNPedia

Notes

A susceptibility locus for myopia in the normal population is linked to the PAX6 gene region on chromosome 11: a genomewide scan of dizygotic twins. A PAX6 gene polymorphism is associated with genetic predisposition to extreme myopia. Maternal transmission effects of the PAX genes among cleft case-parent trios from four populations. AC and AG dinucleotide repeats in the PAX6 P1 promoter are associated with high myopia. PAX6 polymorphisms in 20 Chinese children with supernumerary teeth in the maxillary incisor area.

Source and license

Adapted from rs667773 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.