rs6700998

A SNP on chromosome 1. Its most notable genotype is G;G: 0.83x reduced risk of Atopic Dermatitis.

Gene
None listed
Location
Chr 1152,461,533 (GRCh38)
Highest magnitude
2.0Worth knowing
Tested on
23andMe
Minor allele frequency
41%

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. G;GMost notableGood0.83x reduced risk of Atopic Dermatitis.Worth knowing · 2.035% of people
  2. G;TGoodNormal risk of Atopic Dermatitis.Minor · 1.047% of people
  3. T;TBad1.2x increased risk of Atopic Dermatitis.Worth knowing · 2.018% of people

On SNPedia: (G;G), (G;T), (T;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 11 HapMap populations.

  • AverageG;G 35% G;T 47% T;T 18%
  • European ancestry (Utah)G;G 34% G;T 50% T;T 16%
  • Han Chinese (Beijing)G;G 31% G;T 54% T;T 15%
  • Japanese (Tokyo)G;G 46% G;T 41% T;T 13%
  • Yoruba (Nigeria)G;G 40% G;T 44% T;T 16%
  • African ancestry (Southwest US)G;G 39% G;T 33% T;T 28%
  • Chinese (Denver)G;G 39% G;T 49% T;T 12%
  • Gujarati IndianG;G 20% G;T 60% T;T 20%
  • Luhya (Kenya)G;G 36% G;T 43% T;T 21%
  • Mexican ancestry (Los Angeles)G;G 31% G;T 48% T;T 21%
  • Maasai (Kenya)G;G 30% G;T 51% T;T 19%
  • TuscanG;G 37% G;T 46% T;T 17%

Conditions, medicines and genes

Notes

From SNPedia

Notes

Atopic Dermatitis

G;G

This seems to be a proxy that 23andMe uses for the filaggrin gene variants that they can't measure directly.

G;T

This seems to be a proxy that 23andMe uses for the filaggrin gene variants that they can't measure directly.

T;T

This seems to be a proxy that 23andMe uses for the filaggrin gene variants that they can't measure directly.

Source and license

Adapted from rs6700998 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.