rs6703183

A SNP in the LOC105372898 gene on chromosome 1. Its most notable genotype is C;C: >1.3x risk for ALS for Han Chinese

Gene
LOC105372898
Location
Chr 1209,539,544 (GRCh38)
Highest magnitude
0.0Typical
Tested on
23andMe, AncestryDNA, FamilyTreeDNA
Minor allele frequency
46%

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. C;CMost notableBad>1.3x risk for ALS for Han ChineseTypical · 0.039% of people
  2. C;TBad1.3x risk for ALS for Han ChineseTypical · 0.041% of people
  3. T;TNot ratedNormal risk of ALS for Han ChineseTypical · 0.020% of people

On SNPedia: (C;C), (C;T), (T;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 11 HapMap populations.

  • AverageC;C 39% C;T 41% T;T 20%
  • European ancestry (Utah)C;C 9% C;T 49% T;T 43%
  • Han Chinese (Beijing)C;C 47% C;T 42% T;T 11%
  • Japanese (Tokyo)C;C 49% C;T 45% T;T 6%
  • Yoruba (Nigeria)C;C 77% C;T 23% T;T 0%
  • African ancestry (Southwest US)C;C 56% C;T 35% T;T 9%
  • Chinese (Denver)C;C 43% C;T 41% T;T 16%
  • Gujarati IndianC;C 8% C;T 46% T;T 47%
  • Luhya (Kenya)C;C 64% C;T 35% T;T 2%
  • Mexican ancestry (Los Angeles)C;C 9% C;T 57% T;T 35%
  • Maasai (Kenya)C;C 55% C;T 39% T;T 6%
  • TuscanC;C 14% C;T 44% T;T 42%

Source and license

Adapted from rs6703183 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.