rs6756629

A SNP in the ABCG5 gene on chromosome 2. Its most notable genotype is G;G: common in complete genomics

Gene
ABCG5
Location
Chr 243,837,951 (GRCh38)
Highest magnitude
0.0Typical
Tested on
23andMe, AncestryDNA
Minor allele frequency
7%

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. G;GMost notableGoodcommon in complete genomicsTypical · 0.087% of people

On SNPedia: (G;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 11 HapMap populations.

  • AverageG;G 87%
  • European ancestry (Utah)G;G 85%
  • Han Chinese (Beijing)G;G 97%
  • Japanese (Tokyo)G;G 99%
  • Yoruba (Nigeria)G;G 86%
  • African ancestry (Southwest US)G;G 84%
  • Chinese (Denver)G;G 95%
  • Gujarati IndianG;G 95%
  • Luhya (Kenya)G;G 76%
  • Mexican ancestry (Los Angeles)G;G 72%
  • Maasai (Kenya)G;G 78%
  • TuscanG;G 87%

Conditions, medicines and genes

Other ABCG5 SNPs

All ABCG5 SNPs

Notes

From SNPedia

Show notes, about 150 words

The 23andMe blog reports that the minor allele of this SNP (A) is associated with decreased LDL levels, increased HDL cholesterol levels, and decreased triglyceride levels. DeCode reports that the G allele is associated with a lower risk of gallstone disease (cholelithiasis) . {| border="1" |- !SNP !Rarer allele !LDL !HDL !TG |- | rs6544713 || T || + || || |- | rs2650000 || A || + || || |- | rs471364 || C || || - || |- | rs1800961 || T || || - || |- | rs7679 || C || || - || + |- | rs2967605 || T || || - || |- | rs2409722 || T || || || - |- | rs10903129 || A || - || - || - |- | rs6756629 || A || - || + || - |- | rs12670798 || C || + || + || + |- | rs7395662 || A || - || + || + |- | rs174570 || T || - || - || + |- | rs2271293 || A || - || + || - |- | rs2624265 || C || || || + |- | rs2167079 || T || || + || |- | rs9891572 || T || || + || |- | rs4844614 || T || + || || |- | rs5031002 || G || + || || |- |}

Source and license

Adapted from rs6756629 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.