rs6807362

A SNP in the HTR3C gene on chromosome 3. Its most notable genotype is C;C: increased autism risk

Gene
HTR3C
Location
Chr 3184,060,222 (GRCh38)
Highest magnitude
2.0Worth knowing
Tested on
23andMe
Minor allele frequency
41%

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. C;CMost notableBadincreased autism riskWorth knowing · 2.039% of people
  2. C;GNot ratednormal autism riskMinor · 1.041% of people
  3. G;GGooddecreased autism riskWorth knowing · 2.020% of people

On SNPedia: (C;C), (C;G), (G;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 4 HapMap populations.

  • AverageC;C 39% C;G 41% G;G 20%
  • European ancestry (Utah)C;C 29% C;G 49% G;G 22%
  • Han Chinese (Beijing)C;C 56% C;G 36% G;G 9%
  • Japanese (Tokyo)C;C 57% C;G 36% G;G 7%
  • Yoruba (Nigeria)C;C 15% C;G 44% G;G 42%

Conditions, medicines and genes

Notes

From SNPedia

Notes

rs6807362 is a SNP in the 5-hydroxytryptamine (serotonin) receptor 3, family member C HTR3C gene. In a study of 97 familes with at least one individual with autism, rs6807362 was significantly associated with the disorder (p = 0.0012).

Source and license

Adapted from rs6807362 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.