rs6857249
A SNP in the UGT2B17 gene on chromosome 4. Its most notable genotype is A;A: common in complete genomics
- Gene
- UGT2B17
- Location
- Chr 468,569,184 (GRCh38)
- Highest magnitude
- 0.0Typical
- Tested on
- 23andMe, FamilyTreeDNA
- Minor allele frequency
- 4%
Genotypes
As shown in 23andMe and AncestryDNA files.
On SNPedia: (A;A). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Frequency
Share of each genotype in 7 HapMap populations.
- AverageA;A 96%
- European ancestry (Utah)A;A 98%
- Yoruba (Nigeria)A;A 93%
- African ancestry (Southwest US)A;A 93%
- Gujarati IndianA;A 99%
- Luhya (Kenya)A;A 96%
- Mexican ancestry (Los Angeles)A;A 98%
- Maasai (Kenya)A;A 97%
Related
Notes
From SNPedia
Notes
Deletion of both copies of this gene alters testosterone metabolism making steroid use undetectable. The first page of this thesis claims that the deletion allele has a frequency of 4.8% in Swedes but is completely absent in Koreans. While its abstract claims "it is a common polymorphism with an allele frequency of 29 % in Swedes and 78 % in Koreans."
Source and license
Adapted from rs6857249 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.