rs6968865

A SNP in the LOC101927609 gene on chromosome 7. Its most notable genotype is A;T: Associated with (slightly) increased coffee consumption

Gene
LOC101927609
Location
Chr 717,247,645 (GRCh38)
Highest magnitude
1.2Minor
Tested on
23andMe, AncestryDNA
Minor allele frequency
48%

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. A;ANot ratedNo summary available.Typical · 0.034% of people
  2. A;TMost notableNot ratedAssociated with (slightly) increased coffee consumptionMinor · 1.246% of people
  3. T;TNot ratedAssociated with (slightly) increased coffee consumptionMinor · 1.220% of people

On SNPedia: (A;A), (A;T), (T;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 4 HapMap populations.

  • AverageA;A 34% A;T 46% T;T 20%
  • European ancestry (Utah)A;A 22% A;T 41% T;T 36%
  • Han Chinese (Beijing)A;A 37% A;T 49% T;T 15%
  • Japanese (Tokyo)A;A 56% A;T 38% T;T 7%
  • Yoruba (Nigeria)A;A 22% A;T 57% T;T 22%

Other LOC101927609 SNPs

All LOC101927609 SNPs

Notes

From SNPedia

Notes

rs6968865 is a SNP located near the aryl hydrocarbon receptor AHR gene on ch 7p21. A meta-analysis of four GWAS studies of coffee consumption among a total of ~8,000 coffee drinkers of European ancestry found that the rs6968865(T) was strongly associated with increased consumption (p = 2.3 x 10e-11). The estimated effect was an increase of 0.2 cups a day per allele for both this SNP and one other (rs2472297).

Source and license

Adapted from rs6968865 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.