rs6971091

A SNP in the FAM71F1 gene on chromosome 7. Its most notable genotype is A;A: >2x increased risk for familial obesity

Gene
FAM71F1
Location
Chr 7128,723,233 (GRCh38)
Highest magnitude
0.0Typical
Tested on
23andMe, AncestryDNA, FamilyTreeDNA
Minor allele frequency
15%

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. A;AMost notableBad>2x increased risk for familial obesityTypical · 0.03% of people
  2. A;GBad>2x increased risk for familial obesityTypical · 0.023% of people
  3. G;GGoodnormalTypical · 0.074% of people

On SNPedia: (A;A), (A;G), (G;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 11 HapMap populations.

  • AverageA;A 3% A;G 23% G;G 74%
  • European ancestry (Utah)A;A 6% A;G 35% G;G 58%
  • Han Chinese (Beijing)A;A 2% A;G 23% G;G 76%
  • Japanese (Tokyo)A;A 3% A;G 19% G;G 79%
  • Yoruba (Nigeria)A;A 0% A;G 12% G;G 88%
  • African ancestry (Southwest US)A;A 0% A;G 16% G;G 84%
  • Chinese (Denver)A;A 2% A;G 11% G;G 87%
  • Gujarati IndianA;A 6% A;G 51% G;G 44%
  • Luhya (Kenya)A;A 3% A;G 13% G;G 85%
  • Mexican ancestry (Los Angeles)A;A 0% A;G 28% G;G 72%
  • Maasai (Kenya)A;A 2% A;G 18% G;G 80%
  • TuscanA;A 5% A;G 33% G;G 62%

Conditions, medicines and genes

Notes

From SNPedia

Notes

rs6971091 is a SNP on chromosome 7 that has been linked to obesity. In a study of 400+ patients, rs6971091(A) allele carriers had an odds ratio of at least 2 for obesity defined by both body mass index (BMI) and leptin levels.

Source and license

Adapted from rs6971091 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.