rs6974491

A SNP in the ELMO1 gene on chromosome 7. Its most notable genotype is A;A: Higher risk of coeliac and/or inflammatory bowel disease

Gene
ELMO1
Location
Chr 737,334,906 (GRCh38)
Highest magnitude
1.5Minor
Tested on
23andMe, AncestryDNA
Minor allele frequency
10%

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. A;AMost notableBadHigher risk of coeliac and/or inflammatory bowel diseaseMinor · 1.51% of people
  2. A;GBadHigher risk of coeliac and/or inflammatory bowel diseaseMinor · 1.016% of people
  3. G;GGoodcommon on affy axiom dataTypical · 0.082% of people

On SNPedia: (A;A), (A;G), (G;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 10 HapMap populations.

  • AverageA;A 1% A;G 16% G;G 82%
  • European ancestry (Utah)A;A 3% A;G 25% G;G 72%
  • Han Chinese (Beijing)A;A 0% A;G 2% G;G 99%
  • Japanese (Tokyo)A;A 0% A;G 3% G;G 97%
  • Yoruba (Nigeria)A;A 1% A;G 12% G;G 86%
  • African ancestry (Southwest US)A;A 0% A;G 19% G;G 81%
  • Gujarati IndianA;A 3% A;G 16% G;G 81%
  • Luhya (Kenya)A;A 0% A;G 15% G;G 85%
  • Mexican ancestry (Los Angeles)A;A 0% A;G 31% G;G 69%
  • Maasai (Kenya)A;A 1% A;G 14% G;G 85%
  • TuscanA;A 3% A;G 28% G;G 69%

Other ELMO1 SNPs

All ELMO1 SNPs

Source and license

Adapted from rs6974491 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.