rs6983561

A SNP on chromosome 8. Its most notable genotype is A;A.

Gene
None listed
Location
Chr 8127,094,635 (GRCh38)
Highest magnitude
0.0Typical
Tested on
23andMe, AncestryDNA, FamilyTreeDNA
Minor allele frequency
19%

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. A;AMost notableNot ratedNo summary available.Typical · 0.058% of people

On SNPedia: (A;A). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 4 HapMap populations.

  • AverageA;A 58%
  • European ancestry (Utah)A;A 95%
  • Han Chinese (Beijing)A;A 49%
  • Japanese (Tokyo)A;A 71%
  • Yoruba (Nigeria)A;A 19%

Notes

From SNPedia

Show notes, about 330 words

rs6983561 increases susceptibility to Prostate cancer 1.42 times for carriers of the C allele A common genetic risk factor for colorectal and prostate cancer. Confirmation study of prostate cancer risk variants at 8q24 in African Americans identifies a novel risk locus. 8q24 and prostate cancer: association with advanced disease and meta-analysis. Chromosome 8q24 markers: risk of early-onset and familial prostate cancer. Multiple independent genetic variants in the 8q24 region are associated with prostate cancer risk. Pooled analysis of genetic variation at chromosome 8q24 and colorectal neoplasia risk. Multiple loci with different cancer specificities within the 8q24 gene desert. Clinical utility of five genetic variants for predicting prostate cancer risk and mortality. Evaluation of 8q24 and 17q risk loci and prostate cancer mortality. Novel single nucleotide polymorphism associations with colorectal cancer on chromosome 8q24 in African and European Americans. Prostate cancer risk associated loci in African Americans. Evaluation of the 8q24 prostate cancer risk locus and MYC expression. Significance of common variants on human chromosome 8q24 in relation to the risk of prostate cancer in native Japanese men. WITHDRAWN: Relationships between 8q24 and 17q risk loci and sporadic or latent prostate cancer and the impacts of these loci on the clinicopathologic characteristics of prostate cancer. Estimation of genotype relative risks from pedigree data by retrospective likelihoods. 8q24 sequence variants in relation to prostate cancer risk among men of African descent: a case-control study. Meta-analysis of genome-wide and replication association studies on prostate cancer. A replication study examining three common single-nucleotide polymorphisms and the risk of prostate cancer in a Japanese population. Racial disparities in the association between variants on 8q24 and prostate cancer: a systematic review and meta-analysis.

Source and license

Adapted from rs6983561 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.