rs707284

A SNP in the ERBB4 gene on chromosome 2. Its most notable genotype is A;G.

Gene
ERBB4
Location
Chr 2211,974,321 (GRCh38)
Highest magnitude
0.0Typical
Tested on
23andMe, AncestryDNA, FamilyTreeDNA
Minor allele frequency
45%

Genotypes

Plus strand, as in 23andMe and AncestryDNA files.

  1. A;GMost notableNot ratedNo summary available.Typical · 0.00% of people

SNPedia records rs707284 on the minus strand: (T;C). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 11 HapMap populations.

  • AverageA;G 0%
  • European ancestry (Utah)A;G 0%
  • Han Chinese (Beijing)A;G 0%
  • Japanese (Tokyo)A;G 0%
  • Yoruba (Nigeria)A;G 0%
  • African ancestry (Southwest US)A;G 0%
  • Chinese (Denver)A;G 0%
  • Gujarati IndianA;G 0%
  • Luhya (Kenya)A;G 0%
  • Mexican ancestry (Los Angeles)A;G 0%
  • Maasai (Kenya)A;G 0%
  • TuscanA;G 0%

Conditions, medicines and genes

Other ERBB4 SNPs

All ERBB4 SNPs

Notes

From SNPedia

Notes

linked to schizophrenia with rs7598440, rs839523, and rs707284 Disease-associated intronic variants in the ErbB4 gene are related to altered ErbB4 splice-variant expression in the brain in schizophrenia. Neuregulin 1 in neural development, synaptic plasticity and schizophrenia. A genome-wide investigation of SNPs and CNVs in schizophrenia. Analysis of association between common SNPs in ErbB4 and bipolar affective disorder, major depressive disorder and schizophrenia in the Han Chinese population. The effects of psychosis risk variants on brain connectivity: a review.

Source and license

Adapted from rs707284 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.