rs707746
A SNP in the PSG2 gene on chromosome 19. Its most notable genotype is T;T: common in complete genomics
- Gene
- PSG2
- Location
- Chr 1943,071,794 (GRCh38)
- Highest magnitude
- 0.0Typical
- Tested on
- Not on consumer chips
Genotypes
Plus strand, as in 23andMe and AncestryDNA files.
SNPedia records rs707746 on the minus strand: (A;A). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Related
Conditions, medicines and genes
Notes
From SNPedia
Show notes, about 130 words
https://www.23andme.com/you/community/thread/14602/ http://www.cell.com/AJHG/retrieve/pii/S0002929712003576 Exome Sequencing Identifies FUS Mutations as a Cause of Essential Tremor ... Functional considerations suggest that the pathogenic effects of ET-specific FUS mutations are different from the effects observed when FUS is mutated in amyotrophic lateral sclerosis cases; we have shown that the ET FUS nonsense mutation is degraded by the nonsense-mediated-decay pathway, whereas amyotrophic lateral sclerosis FUS mutant transcripts are not... This snp was flagged as Suspect: Variation suspected to be false positive due to artifacts of the presence of a paralogous sequence in the genome (Musumeci et al. 2010) (Sudmant et al. 2010) or evidence suggested sequencing error or computation artifacts.
Source and license
Adapted from rs707746 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.