rs7105934

A SNP in the LOC102724265 gene on chromosome 11. Its most notable genotype is A;A: 0.48 times lower odds of developing renal cell carcinoma

Gene
LOC102724265
Location
Chr 1169,424,973 (GRCh38)
Highest magnitude
2.1Worth knowing
Tested on
23andMe, AncestryDNA
Minor allele frequency
21%

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. A;AMost notableGood0.48 times lower odds of developing renal cell carcinomaWorth knowing · 2.116% of people
  2. A;GGood0.69 times lower odds of developing renal cell carcinomaWorth knowing · 2.022% of people
  3. G;GGoodcommon in complete genomicsTypical · 0.062% of people

On SNPedia: (A;A), (A;G), (G;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 11 HapMap populations.

  • AverageA;A 16% A;G 22% G;G 62%
  • European ancestry (Utah)A;A <1% A;G 10% G;G 89%
  • Han Chinese (Beijing)A;A 0% A;G 10% G;G 91%
  • Japanese (Tokyo)A;A 0% A;G 4% G;G 97%
  • Yoruba (Nigeria)A;A 52% A;G 37% G;G 10%
  • African ancestry (Southwest US)A;A 40% A;G 47% G;G 12%
  • Chinese (Denver)A;A 0% A;G 14% G;G 86%
  • Gujarati IndianA;A 0% A;G 6% G;G 94%
  • Luhya (Kenya)A;A 58% A;G 38% G;G 4%
  • Mexican ancestry (Los Angeles)A;A 2% A;G 7% G;G 91%
  • Maasai (Kenya)A;A 24% A;G 49% G;G 26%
  • TuscanA;A 1% A;G 21% G;G 78%

Notes

From SNPedia

Notes

23andMe reports that each A allele at rs7105934 is associated with 0.69 times lower odds of developing renal cell carcinoma (a form of kidney cancer).

Source and license

Adapted from rs7105934 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.