rs71180793
A SNP in the OBSCN gene on chromosome 1. Its most notable genotype is -;C: Left ventricular noncompaction possible (likely?)
- Gene
- OBSCN
- Location
- Chr 1228,371,745 (GRCh38)
- Highest magnitude
- 5.0Very important
- Tested on
- Not on consumer chips
Genotypes
As shown in 23andMe and AncestryDNA files.
On SNPedia: (-;C), (C;C). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Related
Conditions, medicines and genes
Notes
From SNPedia
Notes
The rare minor allele of this OBSCN SNP is reported in to be a variant leading to left ventricular noncompaction, acting in a dominant manner (i.e. in heterozygotes). Exome Sequencing of Familial Bipolar Disorder. The minor allele of this SNP is one of 84 rare variants speculated to have an impact (positive or negative; see publication for specific SNP details) on risk for bipolar disorder. The analysis of many more patients is likely to be required to confirm or refute this association.
-;C
See rs71180793 for the link to this type of cardiomyopathy.
Source and license
Adapted from rs71180793 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.