rs7181866

A SNP in the GABPB1 gene on chromosome 15. Its most notable genotype is G;G.

Gene
GABPB1
Location
Chr 1550,318,595 (GRCh38)
Highest magnitude
3.0Important
Tested on
23andMe, AncestryDNA
Minor allele frequency
11%

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. A;AGoodcommon in complete genomicsTypical · 0.074% of people
  2. G;GMost notableNot ratedNo summary available.Important · 3.03% of people

On SNPedia: (A;A), (G;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 10 HapMap populations.

  • AverageA;A 74% G;G 3%
  • European ancestry (Utah)A;A 98% G;G 0%
  • Han Chinese (Beijing)A;A 58% G;G 7%
  • Japanese (Tokyo)A;A 58% G;G 2%
  • Yoruba (Nigeria)A;A 76% G;G 1%
  • African ancestry (Southwest US)A;A 72% G;G 5%
  • Chinese (Denver)A;A 64% G;G 4%
  • Gujarati IndianA;A 91% G;G 1%
  • Luhya (Kenya)A;A 72% G;G 4%
  • Mexican ancestry (Los Angeles)A;A 91% G;G 3%
  • Maasai (Kenya)A;A 62% G;G 4%

Other GABPB1 SNPs

All GABPB1 SNPs

Notes

From SNPedia

Notes

suggesting a positive association between the AG genotype, and possibly the G allele, and the likelihood of being an elite endurance athlete perhaps similar to rs1815739 NRF2 genotype improves endurance capacity in response to training.

Source and license

Adapted from rs7181866 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.