rs7270101

A SNP in the ITPA gene on chromosome 20. Its most notable genotype is C;C: causative. Ribavirin-induced anemia iRibavirin-induced anemia during anti-hepatitis C virus therapy

Gene
ITPA
Location
Chr 203,213,247 (GRCh38)
Highest magnitude
3.3Important
Tested on
23andMe, AncestryDNA
Minor allele frequency
7%

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. A;AGoodNo summary available.Typical · 0.085% of people
  2. C;CMost notableBadcausative. Ribavirin-induced anemia iRibavirin-induced anemia during anti-hepatitis C virus therapyImportant · 3.3<1% of people

On SNPedia: (A;A), (C;C). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 9 HapMap populations.

  • AverageA;A 85% C;C <1%
  • European ancestry (Utah)A;A 74% C;C 0%
  • Han Chinese (Beijing)A;A 100% C;C 0%
  • Japanese (Tokyo)A;A 100% C;C 0%
  • Yoruba (Nigeria)A;A 82% C;C 2%
  • Gujarati IndianA;A 96% C;C 1%
  • Luhya (Kenya)A;A 77% C;C 3%
  • Mexican ancestry (Los Angeles)A;A 90% C;C 0%
  • Maasai (Kenya)A;A 71% C;C 2%
  • TuscanA;A 79% C;C 1%

Other ITPA SNPs

All ITPA SNPs

Source and license

Adapted from rs7270101 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.